Hua Tuo, together with Dong Feng and Zhang Zhongjing, are called the Three Genius Physicians during Jian‘an period (late Han Dynasty). Born in the ancient Anhui, he was an alchemist and a physician in Eastern Han Dynasty. His stories can be found in the "Biographies of Alchemists" of Book of the Later Han, the "Bigraphies of Fangshis and Artisans" of Records of the Three Kingdoms and Biography of Hua Tuo.
The first two books indicated that Hua Tuo is a middle-aged man at the age of almost 100. Book of the Later Han even described Hua Tuo as a celestial being.
When he was young, he traveled and studied in Xuzhou and was familiar with several classic works. Some imperial officials had once recommended him to imperial but he rather healed people in countryside. From time to time, his excellent skills of healing had strengthened his reputation and many people sought medical advice from him.
Hua Tuo was once summoned by Cao Cao (the Emperor Wu of Wei) for healing Cao’s severe headache. But Hua was not willing to stay long in an imperial environement so he refused to go back to Cao by making up an excuse of taking care of his sick wife. Then soon Cao found out the truth and bristled with anger. Therefore Cao detained Hua in the prison. Later when Cao‘s most beloved son Cao Chong was seriously ill, Cao was regret to put Hua to death.
Wu Pu and Fan A were the two disciples of Hua Tuo. Since Fan was good at acupuncture, Hua had taught him the prescription of Qiye Qingnian (Herbal Medicine of "Toxicodendron vernicifluum leaves" and "Sigesbeckia orientalis") that could keep one’s hair black even at an old age. Unsurprisingly, the prescription has been lost for a long time ago.